Po-Li Wei, MD PhD

Colorectal Surgery

• Robotic colorectal surgery
• Laparoscopic surgery
• Colorectal cancer

• English
• Chinese



  • M.D. Medical college, National Taiwan University
  • PhD. Graduate Institute of Clinical Medicine, Taipei Medical University



  • Attending Doctor, General Surgery, En-Chu-Kong Hospital
  • Chief, Colorectal Division, En-Chu-Kong Hospital
  • Chief, General Surgery, En-Chu-Kong Hospital
  • Chief, Colorectal Division, Min-Sheng Hospital
  • Attending Doctor, General Surgery, Taipei Medical University Hospital
  • Chief, Division of General Surgery, Taipei Medical University Hospital
  • Vice Chairman, Department of Surgery, TMU Hospital
  • Chairman, Department of Quality Management, TMU Hospital
  • Assistant Professor, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University



  • I Liu TP, Huang CC, Yeh KT, Ke TW, Wei PL, Yang JR, Cheng YW. Down-regulation of let-7a-5p predicts lymph node metastasis and prognosis in colorectal cancer: Implications for chemotherapy. Surg Oncol. 2016 May 27. pii: S0960-7404(16)30035-4. PMID: 27262492
  • Wei PL, Lin HC, Kao LT, Chen YH, Lee CZ. Diabetes is associated with perforated appendicitis: evidence from a population-based study. Am J Surg. 2016 May 7. pii: S0002-9610(16)30207-0. PMID: 27255780
  • Tai CJ, Huang MT, Wu CH, Wang CK, Tai CJ, Chang CC, Hsieh CI, Chang YJ, Wu CJ, Kuo LJ, Wei PL, Chen RJ, Chiou HY Combination of Two Targeted Medications (Bevacizumab Plus Cetuximab) Improve the Therapeutic Response of Pancreatic Carcinoma. Medicine (Baltimore). 2016 Apr;95(15):e3259. PMID: 27082562
  • Tai CJ, Wang H, Wang CK, Tai CJ, Huang MT, Wu CH, Chen RJ, Kuo LJ, Wei PL, Chang YJ, Chang CC, Chiou HY, Wu CJ. Bevacizumab and cetuximab with conventional chemotherapy reduced pancreatic tumor weight in mouse pancreatic cancer xenografts. Clin Exp Med. 2016 Mar 19. [Epub ahead of print] PMID: 26995061
  • Lee YS, Chin YT, Yang YS, Wei PL, Wu HC, Shih A, Lu YT, Pedersen JZ, Incerpi S, Liu LF, Lin HY, Davis PJ. The combination of tetraiodothyroacetic acid and cetuximab inhibits cell proliferation in colorectal cancers with different K-ras status. Steroids. 2016 Mar 12. [Epub ahead of print] PMID: 26980146
  • Luo JD, Chang YJ, Chang CM, You JF, Wei PL, Chiou CC. GeneGazer: A Toolkit Integrating Two Pipelines for Personalized Profiling and Biosignature Identification. Cancer Genomics Proteomics. 2016 03-04;13(2):141-150. PMID: 26912804
  • Tu CC, Huang CY, Cheng WL, Hung CS, Chang YJ, Wei PL . (Correspondence) Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment. Tumour Biol. 2016 Jan 20. [Epub ahead of print] PMID: 26790437
  • Wei PL, Huang CY, Tai CJ, Batzorig U, Cheng WL, Hunag MT, Chang YJ. Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma. Tumour Biol. 2016 Jun;37(6):8219-27. PMID: 26718209
  • Tu CC, Huang CY, Cheng WL, Hung CS, Uyanga B, Wei PL , Chang YJ The α7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes. Tumour Biol. 2016 Apr;37(4):4421-8. PMID: 26499946
  • Huang CY, Batzorig U, Cheng WL, Huang MT, Chen W, Wei PL (Correspondence), Chang YJ. Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma. Tumour Biol. 2016 Apr;37(4):4295-304. PMID: 26493996
  • Klahan S, Huang CC, Chien SC, Wu MS, Wong HS, Huang CY, Chang WC, Wei PL(Correspondence). Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness. Tumour Biol. 2016 Jan;37(1):583-90. PMID:26232912
  • Ho CT, Chang YJ, Yang LX, Wei PL, Liu TZ, Liu JJ. A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells. PLoS One. 2015 Sep 10;10(9):e0136340. PMID: 26355599
  • Wei PL, Tsai MC, Hung SH, Lee HC, Lin HC, Lee CZ(2015).Risk of new-onset type II diabetes after appendicectomy. Br J Surg. 2015 Sep;102(10):1267-71 PMID:26122401
  • Ke TW, Wei PL(Co-first), Yeh KT, Chen WT, Cheng YW. MiR-92a Promotes Cell Metastasis of Colorectal Cancer Through PTEN-Mediated PI3K/AKT Pathway. Ann Surg Oncol. 2015 Aug;22(8):2649-55. PMID: 25515201
  • Lee CZ, Kao LT, Lin HC, Wei PL(Correspondence). Comparison of clinical outcome between laparoscopic and open right hemicolectomy: a nationwide study. World J Surg Oncol. 2015 Aug 15;13:250. PMID: 26271770
  • Chang YJ, Huang CY, Hung CS, Liu HH, Wei PL(Correspondence). Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells. Tumour Biol. 2015 Jun;36(6):4367-76. PMID: 25618598
  • Lin YC, Wei PL(Co-first), Tsai YT, Wong JH, Chang CM, Wang JY, Hou MF, Lee YC, Chuang HY, Chang WC. Pb2+ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells. Environ Toxicol. 2015 Mar;30(3):315-22. PMID: 24106166
  • Chang YJ, Chen WY, Huang CY, Liu HH, Wei PL(Correspondence). Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway. Tumour Biol. 2015 Mar;36(3):1859-69. PMID: 25431258
  • Chang YJ, Huang CY, Hung CS, Chen WY, Wei PL(Correspondence). GRP78 mediates the therapeutic efficacy of curcumin on colon cancer. Tumour Biol. 2015 Feb;36(2):633-41. PMID: 25277658
  • Chang YJ, Li LT, Chen HA, Hung CS, Wei PL(Correspondence). Silencing survivin activates autophagy as an alternative survival pathway in HCC cells. Tumour Biol. 2014 Oct;35(10):9957-66. PMID: 25008566
  • Wu CT, Chang YJ, Chen MF, Liu JJ, Wei PL(Correspondence), Wang W, Liu HH(2014). Thrombomodulin mediates the migratory ability of hormone-independent prostate cancer cells through the regulation of epithelial-to-mesenchymal transition biomarkers. Tumour Biol. 2014 Jun;35(6):6047-54. PMID: 24633886
  • Liang HH, Hung CS, Wang W, Tam KW, Chang CC, Liu HH, Yen KL, Wei PL(Correspondence) (2014).Single-incision versus conventional laparoscopic appendectomy in 688 patients: a retrospective comparative analysis. Can J Surg. 2014 Jun;57(3):E89-97. PMID: 24869622
  • Tong YS, Wu CC, Bai CH, Lee HC, Liang HH, Kuo LJ, Wei PL, Tam KW. Effect of extraperitoneal bupivacaine analgesia in laparoscopic inguinal hernia repair: a meta-analysis of randomized controlled trials. Hernia. 2014 Apr;18(2):177-83. PMID: 23644775
  • Hung CS, Su HY, Liang HH, Lai CW, Chang YC, Ho YS, Wu CH, Ho JD, Wei PL(Correspondence), Chang YJ. High-level expression of CXCR4 in breast cancer is associated with early distant and bone metastases. Tumour Biol. 2014 Feb;35(2):1581-8. PMID: 24101191
  • Tai CJ, Cheng CW, Su HY, Chen WY, Wu CT, Lin FY, Wang CK, Tai CJ, Wei PL(Correspondence).Thrombomodulin mediates the migration of cervical cancer cells through the regulation of epithelial-mesenchymal transition biomarkers. Tumour Biol. 2014 Jan;35(1):47-54.. PMID: 23881386
  • Hung CS, Liu HH, Liu JJ, Yeh CT, Chang TC, Wu CH, Ho YS, Wei PL(Correspondence), Chang YJ.MicroRNA-200a and -200b Mediated Hepatocellular Carcinoma Cell Migration Through the Epithelial to Mesenchymal Transition Markers. Ann Surg Oncol. 2013 Dec;20 Suppl 3:S360-8. PMID: 22868917
  • Kuo LJ, Hung CS, Chen WY, Chang YJ, Wei PL(Correspondence). Glucose-regulated protein 78 silencing down-regulates vascular endothelial growth factor/vascular endothelial growth factor receptor 2 pathway to suppress human colon cancer tumor growth. J Surg Res. 2013 Nov;185(1):264-72.PMID: 23759331
  • Liang HH, Wei PL, Hung CS, Wu CT, Wang W, Huang MT, Chang YJ. MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. Tumour Biol. 2013 Oct;34(5):3209-18. PMID: 23760980
  • Wei PL, Tu CC, Chen CH, Ho YS, Wu CT, Su HY, Chen WY, Liu JJ, Chang YJ(2013).Shikonin Suppresses the Migratory Ability of Hepatocellular Carcinoma Cells. J Agric Food Chem. 2013 Aug 28;61(34):8191-7. PMID: 23899086
  • Lin CY, Wei PL, Chang WJ, Huang YK, Feng SW, Lin CT, Lee SY, Huang HM. Slow freezing coupled static magnetic field exposure enhances cryopreservative efficiency-a study on human erythrocytes. PLoS One. 2013;8(3):e58988..PMID: 23520546
  • Kuo LJ, Hung CS, Wang W, Tam KW, Lee HC, Liang HH, Chang YJ, Huang MT, Wei PL(Correspondence).Intersphincteric resection for very low rectal cancer: clinical outcomes of open versus laparoscopic approach and multidimensional analysis of the learning curve for laparoscopic surgery. J Surg Res. 2013 Aug;183(2):524-30. PMID: 23465434
  • Wang CC, Tu CC, Wang PC, Lin HC, Wei PL(Correspondence).Outcome comparison between laparoscopic and open appendectomy: evidence from a nationwide population-based study. PLoS One. 2013 Jul 12;8(7):e68662.. PMID: 23874710
  • Wong CS, Chia CF, Lee HC, Wei PL, Ma HP, Tsai SH, Wu CH, Tam KW. Eradication of Helicobacter pylori for prevention of ulcer recurrence after simple closure of perforated peptic ulcer: a meta-analysis of randomized controlled trials. J Surg Res. 2013 Jun 15;182(2):219-26. PMID: 23158404
  • Liao CK, Tsai FC, Fong TH, Hu CM, Wei PL, Su CH. Damage from periorbital ageing to the multilayered structures and resilience of the skin in Chinese population. Int J Exp Pathol. 2013 Jun;94(3):188-94. PMID: 23441675
  • Liang HH, Wang W, Hung CS, Wei PL, Yen KL, Kuo LJ, Tu CC. Branch-type gas in the liver. J Emerg Med. 2013 May;44(5):e363-4. PMID: 23375219
  • Liang HH, Tu CC, Hung CS, Wei PL, Yen KL, Kuo LJ. "Air bubble" in the head after transanal excision of a rectal carcinoma. J Emerg Med. 2013 Feb;44(2):e273-4. PMID: 23158575
  • Wei PL, Keller JJ, Kuo LJ, Lin HC.Increased risk of diabetes following perianal abscess: a population-based follow-up study. Int J Colorectal Dis. 2013 Feb;28(2):235-40. PMID: 22729713
  • Liang HH, Wei PL, Liu WM, Chen CC, Yen KL, Kuo LJ, Hung CS. Free Air in the Abdomen. J Emerg Med. 2013 Jan;44(1):e93-4.. PMID: 22406027
  • Wei PL, Chen CS, Keller JJ, Lin HC. Monthly variation in acute appendicitis incidence: A 10-year nationwide population-based study. J Surg Res. 2012 Dec;178(2):670-6. PMID: 22795352
  • Tai CJ, Chen CS, Hung CS, Kuo LJ, Wei PL, Chiou JF, Hsu CH, Chiou HY, Wu CH. Bevacizumab plus Docetaxel and Cisplatin for Metastatic Breast Cancer: A Pilot Phase II Study. Anticancer Res. 2012 Dec;32(12):5501-6. PMID: 23225458
  • Wei PL, Tu SH, Lien HM, Chen LC, Chen CS, Wu CH, Huang CS, Chang HW, Chang CH, Tseng H, Ho YS(2012).The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate. J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6 PMID: 23361270
  • Hung CS, Liu HH, Huang MT, Cheng CW, Kuo LJ, Ho YS, Wu CH, Chen CM, Wei PL(Correspondence) , Chang YJ. Knockdown survivin expression reduces the efficacy of curcumin treatment in hepatocellular carcinoma cells. Ann Surg Oncol. 2012 Oct;19(11):3547-55. PMID: 22711176
  • Hsu W, Chen CS, Lee HC, Liang HH, Kuo LJ, Wei PL, Tam KW. Preservation versus division of ilioinguinal nerve on open mesh repair of inguinal hernia: a meta-analysis of randomized controlled trials. World J Surg. 2012 Oct;36(10):2311-9. PMID: 22644622
  • Hung CS, Lin SF, Liu HH, Kuo LJ, Li LT, Su HY, Liew PL, Lin FY, Wei PL, Liu DZ, Chang YJ. Survivin-mediated therapeutic efficacy of gemcitabine through glucose-regulated protein 78 in hepatocellular carcinoma. Ann Surg Oncol. 2012 Aug;19(8):2744-52. PMID: 22258814
  • Wei PL, Kuo LJ, Wang W, Lin FY, Liu HH, How T, Ho YS, Huang MT, Wu CH, Chang YJ. Silencing of Glucose-Regulated Protein 78 (GRP78) Enhances Cell Migration Through the Upregulation of Vimentin in Hepatocellular Carcinoma Cells. Ann Surg Oncol. 2012 Jul;19 Suppl 3:S572-9. PMID: 21947694
  • Wei PL, Liu SP, Keller JJ, Lin HC. Volume-outcome relation for acute appendicitis: evidence from a nationwide population-based study. PLoS One. 2012;7(12):e52539. PMID: 23300703
  • Wang W, Chin-Sheng H, Kuo LJ, Wei PL, Lien YC, Lin FY, Liu HH, Ho YS, Wu CH, Chang YJ. NNK enhances cell migration through α7-nicotinic acetylcholine receptor accompanied by increased of fibronectin expression in gastric cancer. Ann Surg Oncol. 2012 Jul;19 Suppl 3:S580-8. PMID: 21969082
  • Wei PL, Keller JJ, Liang HH, Lin HC. Acute appendicitis and adverse pregnancy outcomes: a nationwide population-based study. J Gastrointest Surg. 2012 Jun;16(6):1204-11. PMID: 22404956
  • Kuo LJ, Chiou JF, Tai CJ, Chang CC, Kung CH, Lin SE, Hung CS, Wang W, Tam KW, Lee HC, Liang HH, Chang YJ, Wei PL (Correspondence). Can we predict pathologic complete response before surgery for locally advanced rectal cancer treated with preoperative chemoradiation therapy?. Int J Colorectal Dis. 2012 May;27(5):613-21. PMID: 22080392
  • Tai CJ, Chin-Sheng H, Kuo LJ, Wei PL, Lu HH, Chen HA, Liu TZ, Liu JJ, Liu DZ, Ho YS, Wu CH, Chang YJ. Survivin-mediated cancer cell migration through GRP78 and epithelial-mesenchymal transition (EMT) marker expression in Mahlavu cells. Ann Surg Oncol. 2012 Jan;19(1):336-43. PMID: 21516372