Shih-Hsin Tu, MD

Breast Surgery

SPECIALTY/PRACTICE AREAS：
• Breast surgery
• Endocrine surgery
LANGUAGES SPOKEN：
• English
• Chinese

 

PROFESSIONAL EDUCATION：

• Bachelor of Medicine (M.B.) degree, China Medical University, Taichung, Taiwan

   

ADMINSTRATIVE APPOINTMENTS：

• Vice Superintendent, Taipei Cancer Center
• Associate Professor of Taipei Medical University
• Chief, Breast Medical Center
• Chief, Division of Breast Surgery, Department of surgery, Cathay General Hospital, Taipei, Taiwan

   

PUBLICATIONS：

• Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling. Lin ST, Tu SH, Yang PS6, Hsu SP, Lee WH, Ho CT, Wu CH, Lai YH, Chen MY, Chen LC. J Agric Food Chem. 2016 Sep 14;64(36):6826-37. (SCI)
• Pu-erh tea extract attenuates nicotine-induced foam cell formation in primary cultured monocytes: an in-vitro mechanistic study. J Agric Food Chem. Tu SH*, Chen MY, Chen LC*, Mao YT, Ho CH, Lee WJ, Lin YK, Pan MH, Lo CY, Chen CL, Yen Y, Whang-Peng J, Ho CT, Wu CH, Ho YS. 2016 Apr 27;64(16):3186-95. (*equal-First author) (SCI)
• MSH2 rs2303425 Polymorphism is Associated with Early-Onset Breast Cancer in Taiwan. Hsieh YC, Cho EC, Tu SH, Wu CH, Hung CS, Hsieh MC, Su CT, Liu YR, Lee CH, Ho YS, Chiou HY. Ann Surg Oncol. 2016 Mar 14. [Epub ahead of print] (SCI)
• Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study. Chen LC*, Chen MY, Tu SH*, Pan MH, Lo CY, Ho CT, Wu CH, Ho YS. J Funct Foods 22: 132–144, 2016. (*equal-First author) (SCI)
• Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface. Cheng TC, Tu SH*, Chen LC, Chen MY, Chen WY, Lin YK, Ho CT, Lin SY*, Wu CH, Ho YS. Oncotarget. 2015 Aug 28; 6(25):21283-300. (*equal-Second author) (SCI)
• Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1. Jin G, Lee SW, Zhang X, Cai Z, Gao Y, Chou PC, Rezaeian AH, Han F, Wang CY, Yao JC, Gong Z, Chan CH, Huang CY, Tsai FJ, Tsai CH, Tu SH, Wu CH, Sarbassov dos D, Ho YS, Lin HK. Mol Cell. 2015 Jun 18;58(6):989-1000.(SCI)
• Conceptual structure of the Taiwan Chinese version of the EORTC QLQ-C30. Huang CC, Tu SH, Lien HH, Huang CS, Wang PC, Chie WC. Qual Life Res. 2015 Aug;24(8):1999-2013 (SCI)
• CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan. Hsieh YC, Lee CH, Tu SH, Wu CH, Hung CS, Hsieh MC, Chuang CW, Ho YS, Chiou HY. Carcinogenesis. 2014 Nov; 35(11):2520-5. (SCI)
• Multiclass prediction with partial least square regression for gene expression data: applications in breast cancer intrinsic taxonomy. Huang CC*, Tu SH*, Huang CS, Lien HH, Lai LC, Chuang EY. Biomed Res Int. 2013;2013:248648. (*equal-First author) (SCI)
• Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression. Tu SH, Ho CT, Liu MF, Huang CS, Chang HW, Chang CH, Wu CH, Ho YS. Food Chem. 2013 Nov 15;141(2):1553-61. (SCI)
• Concurrent gene signatures for han chinese breast cancers. Huang CC, Tu SH, Lien HH, Jeng JY, Huang CS, Huang CJ, Lai LC, Chuang EY. PLoS One. 2013 Oct 3;8(10):e76421. (SCI)
• Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues. Huang CS, Ho CT, Tu SH, Pan MH, Chuang CH, Chang HW, Chang CH, Wu CH, Ho YS. J Agric Food Chem. 2013 May 8;61(18):4326-35. (SCI)
• Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development. Tam KW, Ho CT, Lee WJ, Tu SH, Huang CS, Chen CS, Lee CH, Wu CH, Ho YS. Food Chem. 2013 Jun 1;138(2-3):1015-21. (SCI)
• Quercetin Enhances Tamoxifen-induced Antitumor Activity through Down-regulation of Cyclin E2 Expression in Drug-resistant Human Breast Cancer Cells. Tu SH, Yang KC, Ho CD, Huang CS, Chen CH, Chang HW, Chang CH, Wu CH, Ho YS. J Cancer Res Pract 29(4): 167-81, 2013.
• The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate. Wei PL, Tu SH, Lien HM, Chen LC, Chen CS, Wu CH, Huang CS, Chang HW, Chang CH, Tseng H, Ho YS. J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6. (SCI)
• The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate. Wei PL, Tu SH, Lien HM, Chen LC, Chen CS, Wu CH, Huang CS, Chang HW, Chang CH, Tseng H, Ho YS. J Cancer Res Ther. 2012 Oct-Dec;8(4):532-6. (SCI)
• Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population. Huang CC, Tu SH, Lien HH, Jeng JY, Liu JS, Huang CS, Wu YY, Liu CY, Lai LC, Chuang EY. J Transl Med. 2012 Sep 19;10 Suppl 1:S10. (SCI)
• Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway. Chen LC, Tu SH, Huang CS, Chen CS, Ho CT, Lin HW, Lee CH, Chang HW, Chang CH, Wu CH, Lee WS, Ho YS. Breast Cancer Res Treat. 2012 Aug;134(3):989-1004. (SCI)
• In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway. Tu SH, Wu CH, Chen LC, Huang CS, Chang HW, Chang CH, Lien HM, Ho YS. J Agric Food Chem. 2012 Apr 11;60(14):3612-8. (SCI)
• A novel HLA-A2-restricted CTL epitope of tumor-associated antigen L6 can inhibit tumor growth in vivo. Tu SH*, Huang HI*, Lin SI, Liu HY, Sher YP, Chiang SK, Chong P, Roffler S, Tseng GC, Chen HW, Liu SJ. J Immunother. 2012 Apr;35(3):235-44. (*equal-First author) (SCI)
• Changes in quality of life among newly diagnosed breast cancer patients in Taiwan. Cheng SY, Lai YH, Chen SC, Shun SC, Liao YM, Tu SH, Chen CS, Hsiang CY, Chen CM. J Clin Nurs. 2012 Jan;21(1-2):70-9. (SCI)
• A model-based circular binary segmentation algorithm for the analysis of array CGH data. Hsu FH, Chen HI, Tsai MH, Lai LC, Huang CC, Tu SH, Chuang EY, Chen Y. BMC Res Notes. 2011 Oct 10;4:394.
• Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells. Tu SH*, Ku CY, Ho CT, Chen CS, Huang CS*, Lee CH, Chen LC, Pan MH, Chang HW, Chang CH, Chang YJ, Wei PL, Wu CH, Ho YS. Mol Nutr Food Res. 2011 Mar;55(3):455-66. (*equal-First author) (SCI)
• Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells. Lee CH, Chang YC, Chen CS, Tu SH, Wang YJ, Chen LC, Chang YJ, Wei PL, Chang HW, Chang CH, Huang CS, Wu CH, Ho YS. Breast Cancer Res Treat. 2011 Sep;129(2):331-45. (SCI)
• Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins. Chen CS, Lee CH, Hsieh CD, Ho CT, Pan MH, Huang CS, Tu SH, Wang YJ, Chen LC, Chang YJ, Wei PL, Yang YY, Wu CH, Ho YS. Breast Cancer Res Treat. 2011 Jan;125(1):73-87. (SCI)