Chun-Chao Chang, M.D., Ph.D.

Gastroenterology

SPECIALTY/PRACTICE AREAS：
• Gastrointestinal diseases
• Hepatitis
• Digestive Endoscopy
• Abdominal sonography
• Local ablation for liver cancer
LANGUAGES SPOKEN：
• English
• Chinese

 

PROFESSIONAL EDUCATION：

• Taipei Medical University, MD.
• Taipei Medical University Graduate Institute of Medical Sciences, MS

 

ADMINSTRATIVE APPOINTMENTS：

• Director, TMU Research Center for Digestive Medicine, Taipei Medical University (2022.04~Present)
• Professor, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University (2016.02~Present)
• Vice Superintendent, Taipei Medical University Hospital (2017.08~Present)
• Director, Department of Medical Education, Taipei Medical University Hospital (2020.08~2020.11)
• Attending Physician, Department of Internal Medicine, Taipei Medical University Hospital (1996.07~present)
• Director, Department of Internal Medicine, Taipei Medical University Hospital (2010.08~2017.07.31)
• Director, Medical Administration Department (2015.08~2017.07.31)
• Director of the Center of Endoscopy and Sonography, Taipei Medical University Hospital (2000.08~2003.12)
• Director, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital (2003.12~2016.05.01)

 

PUBLICATIONS：

• Chiu CH, Chen MY, Lieu JJ, Chen CC, Chang CC**, Chyau CC, Peng RY, (2023).Inhibitory Effect of Styrylpyrone Extract of Phellinus linteus on Hepatic Steatosis in HepG2 Cells. Int J Mol Sci.(4):3672-.
• Yu SH, Chang CC**, Mai FD, Tsai HY, Liu YC, (2023).Engineered active pure water with reduced hydrogen bonds catalyzes itself in green energy production of oxygen and hydrogen evolution reactions. Chemical Engineering Journal.(470):144379-.
• Chang CC**, Liu CY, Su IC, Lee YJ, Yeh HJ, Chen WC, Yu CJ, Kao WY, Liu YC, Huang CJ Functional Plasmon-Activated Water Increases Akkermansia muciniphila Abundance in Gut Microbiota to Ameliorate Inflammatory Bowel Disease. Int J Mol Sci 2022;23(19):11422-
• Chen PC, Lu YR, Kang YN, Chang CC*, (2022).The Accuracy of Artificial Intelligence in the Endoscopic Diagnosis of Early Gastric Cancer: Pooled Analysis Study. J Med Internet Res.(5):e27694-.
• Chiu CH, Chang CC**, Lin JJ, Chen CC, Chyau CC, Peng RY, (2022).Styrylpyrones from Phellinus linteus Mycelia Alleviate Non-Alcoholic Fatty Liver by Modulating Lipid and Glucose Metabolic Homeostasis in High-Fat and High-Fructose Diet-Fed Mice. Antioxidants (Basel).(11):898-.
• Yua SH, Chang CC**, Mai FD, Yang CP, Liu YC, (2022).Plasmon-activated water can form stronger intermolecular hydrogen bonding with water-soluble alcohols and dissolve more hydrophobic solutes. Chem Eng J.(427):1-8.
• Cheng CC, Chang YF, Ho AS, Sie ZL, Chang JS, Peng CL, Chang CC*, Irradiation Mediates IFNα and CXCL9 Expression in Non-Small Cell Lung Cancer to Stimulate CD8 + T Cells Activity and Migration toward Tumors. Biomedicines 2021;9(10):1349-
• How SC, Lin TH, Chang CC*, Wang SS Examining the effect of bovine serum albumin on the properties and drug release behavior of β-lactoglobulin-derived amyloid fibril-based hydrogels. Int J Biol Macromol 2021;1 84:79-91
• Chou TH, Yeh HJ, Chang CC*, Tang JH, Kao WY, Su IC, Li CH, Chang WH, Huang CK, Sufriyana H, Su EC., (2021). Deep learning for abdominal ultrasound: A computer-aided diagnostic system for the severity of fatty liver. J Chin Med Assoc. (9):842-850.
• Kang YN, Chang CC*, (2021). Response to letter to the editor: Appropriate data synthesis provide reliable evidence regarding efficacy of FOY in preventing post endoscopic retrograde cholangiopancreatography pancreatitis. J Formos Med Assoc.(9):1798-1799.
• Lin YC, Chen CY, Chang CC*, Kang YN Letter: is there no conclusive evidence for the effect of tranexamic acid on mortality in gastrointestinal bleeding?. Aliment Pharm Ther 2021;54(4):523-525
• Yu CJ, Yeh HJ, Chang CC*, Tang JH,Kao WY, Chen WC, Huang YJ, Li CH, Chang WH, Lin YT, Sufriyana H, Su EC Lightweight deep neural networks for cholelithiasis and cholecystitis detection by point-of-care ultrasound. Comput Meth Prog Bio 2021
• Su WC, Kao WY, Chang TK, Tsai HL, Huang CW, Chen YC, Li CC, Hsieh YC, Yeh HJ, Chang CC*, Wang JY., (2021). Stool DNA Test Targeting Methylated Syndecan-2 (SDC2) as a Noninvasive Screening Method for Colorectal Cancer. Biosci Rep. 2021 Jan 29;41(1):BSR20201930. doi: 10.1042/BSR20201930.
• Yu SH, Chang CC**, Mai FD, Tsai HY, Liu YC., (2020). Catalytic Reduction Utilizing Innovative Plasmon-Activated Water and Its Vapor. Acs Sustain Chem Eng 2020 Dec 30; 9(1) 411-142, doi: https://doi.org/10.1021/acssuschemeng.0c07535
• Su YF, Cheng SW, Chang CC*, Kang YN, (2020). Efficacy and safety of traction-assisted endoscopic submucosal dissection: a meta-regression of randomized clinical trials. Endoscopy. (5):338-348.
• Chyau CC, Wang HF, Zhang WJ, Chen CC, Huang SH, Chang CC*, Peng RY, (2020). Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway. Int J Mol Sci. 2020 Jan 6;21(1):360. doi: 10.3390/ijms2101036
• Cheng CC, Yang BL, Chen WC, Ho AS, Sie ZL, Lin HC, Chang CC*, (2020). STAT3 Mediated miR-30a-5p Inhibition Enhances Proliferation and Inhibits Apoptosis in Colorectal Cancer Cells. Int J Mol Sci. 2020 Oct 3;21(19):7315. doi: 10.3390/ijms21197315.
• Lee PL, Yang KS, Tsai HW, Hou SK, Kang YN, Chang CC*, (2020). Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials. Aliment Pharmacol Ther. 2020 Jun;51(11):1004-1013. doi: 10.1111/apt.15761.
• Chiua YJ, Chena SC, Kang YN, Houa SK, Chao CC, Chang CC*, (2020). Efficacy of gabexate mesilate in preventing post endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis of randomized clinical trials Author links open overlay panel. Journal of the Formosan Medical Association. J Formos Med Assoc. 2020 Nov 9; S0929-6646(20)30534-9. doi: 10.1016/j.jfma.2020.10.034. Online ahead of print.
• Cheng SW, Chang CC**, Su YF, Kang YN, (2019). How does lesion size affect the pooled effect of traction-assisted endoscopic submucosal dissection on procedure time? A meta-regression. World J Surg Oncol. 2019 Sep 10;17(1):157. doi: 10.1186/s12957-019-1699-0.
• Kao WY, Tiong C, Chang CC*, (2019). A rare cause of hematochezia after colonoscopy. Dig Liver Dis.(3):452-452.
• Hsieh PH, Su HY, Lin CY, Kang YN, Chang CC*, (2019). Infection rate among nutritional therapies for acute pancreatitis: A systematic review with network meta-analysis of randomized controlled trials. PLoS One. 2019 Jul 10;14(7):e0219151. doi: 10.1371/journal.pone.0219151. eCollection 2019.
• Chen HC, Chang CC, Yang KH, Mai FD, Tseng CL, Chen LY, Hwang BJ, Liu YC, (2018).Polypyrrole electrode with a greater electroactive surface electrochemically polymerized in plasmon-activated water. Journal of the Taiwan Institute of Chemical Engineers.(82):252-260.
• Lin P, Chang CC, Yuan KC, Yeh HJ, Fang SU, Cheng T, Teng KT, Chao KC, Tang JH, Kao WY, Lin PY, Liu JS, Chang JS, (2018).Red Blood Cell Aggregation-Associated Dietary Pattern Predicts Hyperlipidemia and Metabolic Syndrome. Nutrients.(8):E1127-.
• Chen HC, Chang CC, Yang KH, Mai FD, Tseng CL, Chen LY, Hwang BJ, Liu YC, (2018).Polypyrrole electrode with a greater electroactive surface electrochemically polymerized in plasmon-activated water. Journal of the Taiwan Institute of Chemical Engineers.(82):252-260.
• Lu JH, Peng BY, Chang CC, Dubey NK, Lo WC, Cheng HC, Wang JR, Wei HJ, Deng WP, (2018).Tumor-Targeted Immunotherapy by Using Primary Adipose-Derived Stem Cells and an Antigen-Specific Protein Vaccine. Cancers (Basel).(11):E446-.
• Chen HC, Cheng CY, Chen LY, Chang CC, Yang CP, Mai FD, Liao WC, Chang HM, Liu YC, (2018).Plasmon-activated water effectively relieves hepatic oxidative damage resulting from chronic sleep deprivation. RSC Advances.():9618-9626.
• Kao WY, Su CW, Fang SU, Tang JH, Chang CC, Liu JD, (2018).Determination of the predictive factors for significant liver fibrosis assessed through transient elastography. Advances in Digestive Medicine.():-.
• Liou JM, Chen PY, Luo JC, Lee JY, Chen CC, Fang YJ, Yang TH, Chang CY, Bair MJ, Chen MJ, Hsu YC, Hsu WF, Chang CC, Lin JT, Shun CT, El-Omar EM, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium., (2018).Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection. Efficacies of Genotypic Resistance-Guided vs Empirical Therapy for Refractory Helicobacter pylori Infection.(4):1109-1119.
• Cheng CC, Liao PN, Ho AS, Lim KH, Chang J, Su YW, Chen CG, Chiang YW, Yang BL, Lin HC, Chang YC, Chang CC, Chang YF., (2018).STAT3 exacerbates survival of cancer stem-like tumorspheres in EGFR-positive colorectal cancers: RNAseq analysis and therapeutic screening. J Biomed Sci.(1):60-.
• Cheng HC, Liou JM, Luo JC, Chiu CT, Wu MS, Lee YC, Wu CY, Wu DC, Hsu PI, Chang CC, Chang WL, Lin JT, Sheu BS, (2018).The implementation of the consensus on the management of Helicobacter pylori and barriers to consensus. Helicobacter.(5):e12533-.
• Kao WY, Su CW, Tan EC, Lee PC, Chen PH, Tang JH, Huang YH, Huo TI, Chang CC, Hou MC, Lin HC, Wu JC, (2018).Proton Pump Inhibitors and Risk of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B or C. Hepatology. 2019 Mar;69(3):1151-1164.
• Liou JM, Chen PY, Kuo YT, Wu MS, Liou JM, Lee YC, Chen MJ, Lin JT, Wu CY, Wu JY, Chen CC, Lin CH, Fang YR, Bair MJ, Luo JC, Wu MS, Cheng TY, Tseng PH, Chiu HM, Chang CC, Yu CC, Chiu MC, Chen YN, Hu WH, Chou CK, Tai CM, Lee CT, Wang WL, Chang WS, (2018).Toward population specific and personalized treatment of Helicobacter pylori infection. J Biomed Sci. 2018 Oct 2;25(1):70.
• Fang KC, Kao WY, Su CW, Chen PC, Lee PC, Huang YH, Huo TI, Chang CC, Hou MC, Lin HC, Wu JC, (2018).The Prognosis of Single Large Hepatocellular Carcinoma Was Distinct from Barcelona Clinic Liver Cancer Stage A or B: The Role of Albumin-Bilirubin Grade. Liver Cancer.(4):335-358.