I-Wen Wu, MD

Nephrology

• Edema
• Proteinuria
• Acute/chronic kidney failure
• Diabetic kidney disease
• Cystic kidney disease
• Hemodialysis
• Peritoneal dialysis
• Kidney transplantation
• English
• Spanish
• Chinese

 

PROFESSIONAL EDUCATION：

• 1992-1998 M.D., College of Medicine, University of Buenos Aires, Argentina.

 

ADMINSTRATIVE APPOINTMENTS：

• 2000- 2005: Residentship and fellowship, Department of Internal Medicine, Chang Gung Memorial Hospital, Linkuo Medical Center, Taiwan.
• 2005-2023: Attending Physician, Division of Nephrology, Chang Gung Memorial Hospital, Linkuo Center (2005-2006) and Keelung (2007 to 2023), Taiwan.
• 2017-2023: Director of Department of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
• 2021-2023: Deputy Director of Department of Medical Research and Development, Chang Gung Memorial Hospital, Keelung, Taiwan.
• 2022-2023: Clinical Professor and Vice-Director, Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
• 2023-2024: Secretary General, Taipei Medical University, Taiwan.
• 2023 to present: Attending Physician, Division of Nephrology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
• 2024 to present: Associate Professor, Taipei Medical University.
• 2024 to present: Director of Department of Nephrology, Taipei Medical University Hospital.
• 2024 to present: Director of Department of Medical Research, Taipei Medical University Hospital.
• 2020-2022: Deputy Secretary-General, Taiwan Society of Nephrology
• 2023 to present: Director, International Affairs and Cooperation, Taiwan Society of Nephrology
• 2024 to present: Deputy Director, Diversity and Equity Committee of Asian Pacific Society Nephrology.

 

PUBLICATIONS：

• Wu IW, Wang SY, Hsu KH, Lee CC, Sun CY, Tsai CJ, Wu MS*. Multidisciplinary predialysis education decreases the incidence of dialysis and reduces mortality—a controlled cohort study based on the NKF/DOQI guidelines. Nephrol Dial Transplant, 2009; 24 (11):3426-33.
• Wu IW, Hung MJ, Chen YC, Hsu HJ, Cherng WJ, Chang CJ, Wu MS*. Ventricular Function and All-Cause Mortality in Chronic Kidney Disease Patients with Angiographic Coronary Artery Disease, J Nephrol, 2010; 23 (2):181-8.
• Wu IW, Hsu KH, Lee CC, Sun CY, Hsu HJ, Tsai CJ, Tzen CY, Wang YC, Lin CY, Wu MS*. p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease. Nephrol Dial Transplant, 2011; 26:938-947.
• Wu IW, Hsu KH, Hsu HJ, Lee CC, Sun CY, Tsai CJ, Wu MS*. Serum free p-cresyl sulfate levels predict cardiovascular and all-cause mortality in elderly hemodialysis patients- A prospective cohort study. Nephrol Dial Transplant, 2012; 27(3):1169-75.
• Wu IW, Hsu KH, Sun CY, Tsai CJ, Wu MS, Lee CC*. Oral adsorbent AST-120 potentiates the effect of erythropoietin-stimulating agents in stage 5 chronic kidney disease patients: A randomized crossover study. Nephrol Dial Transplant, 2014; 29:1719-27.
• Lin CN, Wu IW, Huang YF, Peng SY, Huang YC, Ning HC*. Measuring serum total and free indoxyl sulfate and p-cresyl sulfate in chronic kidney disease using UPLC-MS/MS. J Food Drug Anal. 2019, 27, 502-509.
• Wu IW, Lin CY, Chang LC, Lee CC, Chiu CY, Hsu HJ, Sun CY, Chen YC, Kuo YL, Yang CW, Gao SS, Hsieh WP, Chung WH, Lai HC, Su SC*. Gut Microbiota as Diagnostic Tools for Mirroring Disease Progression and Circulating Nephrotoxin Levels in Chronic Kidney Disease: Discovery and Validation Study. Int J Biol Sci. 2020; 16(3):420-434.
• Wu IW, Gao SS, Chou HC, Yang HY, Chang LC, Kuo YL, Dinh MCV, Chung WH, Yang CW, Lai HC, Hsieh WP, Su SC*. Integrative metagenomic and metabolomic analyses reveal severity-specific signatures of gut microbiota in chronic kidney disease. Theranostics. 2020, 10(12), 5398-5411.
• Wu IW, Lee CC, Hsu HJ, Sun CY, Chen YC, Yang KJ, Yang CW, Chung WH, Lai HC, Chang LC, Su SC*. Compositional and functional adaptations of intestinal microbiota and related metabolites in CKD patients receiving dietary protein restriction. Nutrients. 2020, 12, 2799:1-16.
• Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC*, Sytwu HK*, Tsai TF*. Discovery of a Biomarker Signature that Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Crosstalk. Diabetes Care. 2022; 45(6):e102-e104
• Hsu CK, Su SC, Chang LC, Yang KJ, Lee CC, Hsu HJ, Chen YT, Sun CY, Wu IW*. Oral Absorbent AST-120 Is Associated with Compositional and Functional Adaptations of Gut Microbiota and Modification of Serum Short and Medium-Chain Fatty Acids in Advanced CKD Patients. Biomedicines. 2022;10(9):2234.
• Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Chan YH, Chen JH, Hsu PW, Pan HC, Hsu HJ, Chen CY, Lee CC, Shyu YC, Lin CL, Cheng ML, Lai CC*, Sytwu HK*, Tsai TF*. Discovering a trans-omics biomarker signature that predisposes high risk diabetic patients to diabetic kidney disease. NPJ Digit Med. 2022;2;5(1):166.
• Wu IW, Wu YL, Yang HY, Hsu CK, Chang LC, Twu YC, Chang YL, Chung WH, Yang CW, Hsieh WP, Su SC*. Deep immune profiling of patients with renal impairment unveils distinct immunotypes associated with disease severity. Clinical Kidney Journal. 2023;16(1):78–89.
• Wu IW, Chang LC, Wu YL, et al. Gut flora metagenomic analysis coupled with metabolic and deep immune profiling in chronic kidney disease. Nephrol Dial Transplant. 2024; Jul 31;39(8):1333-1343.