PUBLICATIONS
1.  Psychoendocrinoimmunology: Alternation of immunomodulatory system and insulin resistance in bipolar disorder
• Hyperinsulinaemia associated with beta-adrenoceptor antagonist in medicated bipolar patients during manic episode. Tsai SY*, Lee HC, Chen CC (2007) Progress in Neuropsycho- pharmacology & Biological Psychiatry, 31, 1038-1043.
• Hyperinsulinemia associated with overweight medicated bipolar patients during full remission. Chung KH, Tsai SY * (2010) Psychiatry Clinical Neuroscience, 64, 620-624.
• Soluble interleukin-6 receptor level reflecting the illness activity in bipolar disorder. Tsai SY*, Lee CH, Huang SH, Chung KH, Chen PH (2014) Australian and New Zealand Journal of Psychiatry, 48, 382-383.
• Inflammatory markers and their relationships with leptin and insulin from acute mania to full remission in bipolar disorder. Tsai SY*, Chung KH, Wu JY, Kuo CJ, Lee HC, Huang SH (2012) Journal of Affective Disorders, 136, 110-116.
• Persistent inflammation and its relationship to leptin and insulin in phases of bipolar disorder from acute depression to full remission. Tsai SY*, Chung KH, Huang SH, Chen PH, Lee HC, Kuo CJ (2014) Bipolar Disorder, 16, 800-808.
• Antibody profiling of bipolar disorder using Escherichia coli proteome microarrays. Chen PC, Syu GD, Chung KH, Ho YH, Chung FH, Chen PH, Lin JM, Chen YW, Tsai SY*, Chen CS* (2015) Molecular Cell Proteomics, 14, 510-518.

2.  Risk and protective factors for mortality, particularly circulatory mortality, in patients with psychiatric disorders
• A retrospective analysis of risk and protective factors for natural death in bipolar disorder. Tsai SY*, Lee CH, Kuo CJ, Chen CC (2005) Journal of Clinical Psychiatry, 66, 1586-1591.
• Risk factors for completed suicide in schizophrenia. Kuo CJ, Tsai SY, Lo CH, Wang YP, Chen CC (2005) Journal of Clinical Psychiatry, 66, 579-585.
• Risk factors for completed suicide in bipolar disorder. Tsai SY*, Kuo CJ, Chen CC, Lee HC (2002) Journal of Clinical Psychiatry, 63, 469-476.
• Elevated aspartate and alanine aminotransferase levels and natural death among patients with methamphetamine dependence. Kuo CJ, Tsai SY, Liao YT, Conwell Y, Lee WC, Huang MC, Lin SK, Chen CC, Chen WJ (2012) PLOS ONE, 7, e29325.
• Physiological characteristics of patients with schizophrenia prematurely dying from circulatory diseases. Chen PH, Tsai SY*, Kuo CJ, Chung KH, Huang SH, Chen CC (2015) Asia Pac Psychiatry (2015) doi: 10.1111/appy.12207.

3.  Bipolar disorder in late life
• Cognitive impairment in later life of early-onset bipolar disorder. Tsai SY*, Lee HC, Chen CC, Huang YL (2007) Bipolar Disorders, 9, 868-875.
• Cognitive dysfunction and medical morbidity in elderly outpatients with bipolar disorder. Tsai SY*, Kuo CJ, Chung KH, Huang YL, Lee HC, Chen CC (2009) American Journal of Geriatric Psychiatry, 17, 1004-1011.
• Volumetric reduction in various cortical regions of elderly patients with early-onset and late-onset mania. Huang SH, Tsai SY*, Hsu JL, Huang YL (2011) International Psychogeriatics, 23, 149-154.
• The Risk Factor of Elderly Patients with Bipolar Disorder Having Cerebral Infarction. Huang SH, Chung KH, Hsu JL, Wu JY, Huang YL, Tsai SY* (2012) Journal of Geriatric Psychiatry and Neurology, 25, 15-19.
• Neuroprogressive effects of lifetime illness duration in older adults with bipolar disorder. Gildengers AG, Chung KH, Huang SH, Begley A, Aizenstein HJ, Tsai SY* (2014). Bipolar Disorder, 16, 617-623.
• Psychological outcomes and medical morbidity of patients with bipolar disorder and co-occurring alcohol use disorder. Tang HC, Chen PH, Chung KH, Kuo CJ, Huang SH, Tsai SY* (2015) Journal of Dual Diagnosis, 11, 184-188.
• High serum sodium level in affective episode associated with coronary heart disease in old adults with bipolar disorder. Chen PH, Gildengers AG, Lee CH, Chen ML, Kuo CJ, Tsai SY* (2016) International Journal of Psychiatry Medicine, 50(4), 422-433.