PROFESSIONAL EDUCATION
‧Board Certification: Assistant professor, Pulmonologist, Internalist, Medicine, Sleep
Medicine
‧Clinical Fellow: Fellowship of Pulmonary and Critical Care Medicine, Department of
Thoracic Medicine II, Chang Gung Memorial Hospital (2001 to 2003)
‧Residency: Resident Training, Department of Internal Medicine, Chang Gung Memorial
Hospital (1998 to 2001)
‧Internship: Veterans General Hospital-Taipei (1995 to 1996)
‧Medical Education: School of Medicine, Taipei Medical University (1989 to 1996)
ADMINSTRATIVE APPOINTMENTS
‧Specialist, Sleep Center, Taipei Medical University Hospital
‧Specialist, Sleep Center, Taipei Medical University-Shuang-Ho Hospital
‧Assistant Professor, School of Respiratory Therapy, College of Medicine, Taipei Medical
University
‧Assistant Professor, Department of Internal Medicine, School of Medicine, College of
Medicine, Taipei Medical University
‧Attending Physician, Division of Pulmonary Medicine, Department of Internal Medicine,
Taipei Medical University-Shuang-Ho Hospital
PUBLICATIONS
‧Churg-Strauss Syndrome After Corticosteroid Withdrawal in Asthma Patients: Report of
Two Cases not Related to Ieukotriene Receptor Antagonists
Yang MC, Liu WT, Lin HC, Huang CJ, Huang SF, Kuo HP*. Churg-Strauss Syndrome After
Corticosteroid Withdrawal in Asthma Patients: Report of Two Cases not Related to
Ieukotriene Receptor Antagonists, Thoracic Medicine 2003; 18(3):251-8
‧A Case of Difficult Asthma: Churg-Strauss Syndrome
Huang CJ, Liu WT, Lin CL, Chen YM, Wang CH, Kuo HP*. A Case of Difficult Asthma:
Churg-Strauss Syndrome, Thoracic Medicine 2003; 18(3):275-9
‧Zafirlukast improves pulmonary function in patients with moderate persistent asthma
receiving regular inhaled steroids: a prospective randomized control study
Huang CJ, Wang CH, Liu WT, Yang MC, Lin HC, Yu CT, Shiao CJ, Tan CC, Yang CK, Kuo HP*.
Zafirlukast improves pulmonary function in patients with moderate persistent asthma
receiving regular inhaled steroids: a prospective randomized control study, Chang Gung
Medical Journal 2003; 26(8):554-60
‧Safety of the Methacholine Challenge Test in Patients with Severe Airway Obstruction
Chou PC, Lin CL, Liu WT, Lin HC, Kuo HP*. Safety of the Methacholine Challenge Test in
Patients with Severe Airway Obstruction, Thoracic Medicine 2003; 18(4):329-37
‧Diagnostic value of endobronchial ultrasound-guided transbronchial lung biopsy in
peripheral lung cancers
Yang MC, Liu WT, Wang CH, Lin HC, Chen HC, Chou CL, Hsueh S, Kuo HP*. Diagnostic value
of endobronchial ultrasound-guided transbronchial lung biopsy in peripheral lung cancers.
Journal of the Formosan Medical Association 2004; 103(2):124-9.
‧Predicting Value of Abdominal Perfusion Pressure and Plasma Renin Activity in
Mechanically Ventilated Patients
Liu WT, Yang MC, Huang CJ, Lin HC, Wang CH, Kuo HP*. Predicting Value of Abdominal
Perfusion Pressure and Plasma Renin Activity in Mechanically Ventilated Patients, Thoracic
Medicine 2004; 19(2):99-108
‧Eosinophils from Asthmatics Release IL-5 in an Autocrine Fashion to Prevent Apoptosis
Through Upregulation of Bcl-2 Expression
Huang CD, Wang CH, Liu CY, Lin SM, Chou CL, Liu WT, Lin HC, Kuo HP*. Eosinophils from
Asthmatics Release IL-5 in an Autocrine Fashion to Prevent Apoptosis Through
Upregulation of Bcl-2 Expression, Journal of Asthma 2005; 42(5): 395-403.
‧The Clinical Use of an Internet-based Asthma Teleconsultation System
Chang ML, Liu WT, Wang CH, Kuo HP*. The Clinical Use of an Internet-based Asthma
Teleconsultation System, Thoracic Medicine 2007; 22(1):1-12
‧The concertration-dependent chemokine release and pro-apoptotic effects of
neutrophil-derived x-defensin-1 on human bronchial and alveolar epithelial cells
Liu CY, Lin HC, Yu CT, Lin SM, Lee KY, Chen HC, Chou CL, Huang CD, Chou PC, Liu WT, Wang
CH, Kuo HP* The concertration-dependent chemokine release and pro-apoptotic effects
of neutrophil-derived x-defensin-1 on human bronchial and alveolar epithelial cells, Life
Science 2007; 80(8):749-58.
‧Apoptosis-dependent and –independent mechanisms mediate the phagocytic
recognition/clearance of the HL60-aitransfectants with prolonged survival
Chou CL, Chiang LL, Yu CT, Chen HC, Lee KY, Lin SM, Huang CD, Liu WT, Chou PC, Wang CH,
Lin HC, Kuo HP, Liu CY* Apoptosis-dependent and –independent mechanisms mediate the
phagocytic recognition/clearance of the HL60-aitransfectants with prolonged survival,
Inflammation Research 2007; 56(5):195-203.
‧Efficacy of a cell phone-based exercise programme for COPD
Liu WT, Wang CH, Lin HC, Lin SM, Lee KY, Lo YL, Hung SH, Chang YM, Chung KF, Kuo HP*.
Efficacy of a cell phone-based exercise programme for COPD, European Respiratory
Journal 2008; 32(3):651-9.
‧Matrix metalloproteinase-1 polymorphism is associated with persistent airway
obstruction in asthma in the Taiwanese population
Huang CD, Lin SM, Chang PJ, Liu WT, Wang CH, Liu CY, Lin HC, Hsieh LL, Kuo HP*. Matrix
metalloproteinase-1 polymorphism is associated with persistent airway obstruction in
asthma in the Taiwanese population. Journal of Asthma 2009; 46(1):41-46.
‧Predictive factors for mortality among non-HIV-infected patients with pulmonary
tuberculosis and respiratory failure
Lin SM, Wang TY, Liu WT, Chang CC, Lin HC, Liu CY, Wang CH, Huang CD, Lee KY, Kuo HP*.
Predictive factors for mortality among non-HIV-infected patients with pulmonary
tuberculosis and respiratory failure, The international journal of tuberculosis and lung
disease 2009; 13(3):335-340.
‧Diagnostic value of endobronchial ultrasonography for pulmonary tuberculosis
Lin SM, Chung FT, Huang CD, Liu WT, Kuo CH, Wang CH, Lee KY, Liu CY, Lin HC, Kuo HP*.
Diagnostic value of endobronchial ultrasonography for pulmonary tuberculosis, The
Journal of thoracic and cardiovascular surgery 2009; 138(1):179-184.
‧A mobile telephone-based interactive self-care system improves asthma control
Liu WT, Huang CD, Wang CH, Lee KY, Lin SM, Kuo HP*. A mobile telephone-based
interactive self-care system improves asthma control, European Respiratory Journal 2011;
37(2):310-317
‧Reduced nuclear factor-kB repressing factor: a link toward systemic inflammation in COPD
Lee KY, Ho SC, Chan YF, Wang CH, Huang CD, Liu WT, Lin SM, Lo YL, Chang YL, Kuo LW, Kuo
HP. Reduced nuclear factor-kB repressing factor: a link toward systemic inflammation in
COPD, European Respiratory Journal. 2012; 40(4):863-873.
‧Nocturnal CPAP improves walking capacity in COPD patients with obstructive sleep
apnoea
Wang TY, Lo YL, Lee KY, Liu WT, Lin SM, Lin TY, Ni YL, Wang CY, Ho SC, Kuo HP. Nocturnal
CPAP improves walking capacity in COPD patients with obstructive sleep apnoea.
Respiratory Research. 2013 Jun 19; 14(1):66.
‧Comparative proteomics of inhaled silver nanoparticles in healthy and allergen provoked
mice
Su CL, Chen TT, Chang CC, Chuang KJ, Wu CK, Liu WT, Ho KF, Lee KY, Ho SC, Tseng HE,
Chuang HC, Cheng TJ. Comparative proteomics of inhaled silver nanoparticles in healthy
and allergen provoked mice. International Journal of Nanomedicine. 2013 Aug 5; 2013(8):
2783-2799.
‧Chronic cough and obstructive sleep apnea in a sleep laboratory-based pulmonary
practice
Wang TY, Lo YL, Liu WT, Lin SM, Lin TY, Kuo CH, Chung FT, Chou PC, Chang PJ, Ni YL, Ho SC,
Lin HC, Wang CH, Yu CT, Kuo HP. Chronic cough and obstructive sleep apnea in a sleep
laboratory-based pulmonary practice. Cough. 2013 Nov 5;9(1):24.
‧Air pollution exposure and osteoporosis among retired workers with chronic obstructive
pulmonary disease
(Non-SCI) Lee KY, Liu WT, Kuo HP, Wang CH, Chuang HC, Chen TT, Ho SC, Chuang KJ. Air
pollution exposure and osteoporosis among retired workers with chronic obstructive
pulmonary disease. Occupational Medicine & Health Affairs. 2014 Jun 23
‧Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses
Pan CH, Liu WT, Bien MY, Lin IC, Hsiao TC, Ma CM, Lai CH, Chen MC, Chuang KJ, Chuang HC. Effects of size and surface of zinc oxide and aluminum-doped zinc oxide nanoparticles on cell viability inferred by proteomic analyses. International Journal of Nanomedicine. 2014 Aug 2;9:3631-43.
‧Physicochemical and biological characterization of single-walled and double-walled carbon nanotubes in biological media
Liu WT, Bien MY, Chuang KJ, Chang TY, Jones T, BéruBé K, Lalev G, Tsai DH, Chuang HC,
Cheng TJ. Physicochemical and biological characterization of single-walled and
double-walled carbon nanotubes in biological media. Journal of Hazardous Materials.
2014 Sep 15;280:216-25.
‧Inter-alpha-trypsin inhibitor heavy chain 4: a novel biomarker for environmental exposure to particulate air pollution in patients with chronic obstructive pulmonary disease
Lee KY, Feng PH, Ho SC, Chuang KJ, Chen TT, Su CL, Liu WT, Chuang HC. Inter-alpha-trypsin
inhibitor heavy chain 4: a novel biomarker for environmental exposure to particulate air
pollution in patients with chronic obstructive pulmonary disease. International Journal of
Chronic Obstructive Pulmonary Disease. 2015 Apr 24;10(1):831-41.
‧Effects of commuting mode on air pollution exposure and cardiovascular health among young adults in Taipei, Taiwan
Liu WT, Ma CM, Liu IJ, Han BC, Chuang HC, Chuang KJ. Effects of commuting mode on air
pollution exposure and cardiovascular health among young adults in Taipei, Taiwan.
International Journal of Hygiene and Environmental Health. 2015 May; 218(3):319-323
‧Low bone mineral density in COPD patients with osteoporosis is related to low daily physical activity and high COPD assessment test scores
Liu WT, Kuo HP, Liao TH, Chiang LL, Chen LF, Hsu MF, Chuang HC, Lee KY, Huang CD, Ho SC. Low bone mineral density in COPD patients with osteoporosis is related to low daily physical activity and high CAT scores. International Journal of Chronic Obstructive Pulmonary Disease. 2015 Sep 1;10:1737-44
‧Proteoglycan 4 is a diagnostic biomarker for COPD.
Lee KY, Chuang HC, Chen TT, Liu WT, Su CL, Feng PH, Chiang LL, Bien MY. Proteoglycan 4 is
a diagnostic biomarker for COPD. International Journal of Chronic Obstructive Pulmonary
Disease. 2015 Sep 18; 10:1999-2007
‧The association of annual air pollution exposure with blood pressure among patients with sleep-disordered breathing
Liu WT, Lee KY, Lee HC, Chuang HC, Wu D, Juang JN, Chuang KJ. The association of annual air pollution exposure with blood pressure among patients with sleep-disordered breathing. Science of The Total Environment. 2016 Feb 1;543(Pt A):61-66
‧A 65nm CMOS low power impulse radar system for human respiratory feature extraction and diagnosis on respiratory diseases
Tseng ST, Kao YH, Peng CC, Liu JY, Chu SC, Hong GF, Hsieh CH, Hsu KT, Liu WT, Huang YH, Huang SY, Chu TS. A 65nm CMOS low power impulse radar system for human respiratory feature extraction and diagnosis on respiratory diseases. (IEEE) Transactions on Microwave Theory and Techniques. 2016 April; 64(4):1029-1041
‧Associations of autophagy with lung diffusion capacity and oxygen saturation in severe COPD: effects of particulate air pollution
Lee KY, Chiang LL, Ho SC, Liu WT, Chen TT, Feng PH, Su CL, Chuang KJ, Chang CC, Chuang HC. Associations of autophagy with lung diffusion capacity and oxygen saturation in severe COPD: effects of particulate air pollution. International Journal of Chronic Obstructive Pulmonary Disease. 2016 Jul 11; 11:1569-78
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