Meng -Huang Wu, MD, PhD

Orthopedics

SPECIALTY/PRACTICE AREAS：
• Spine endoscopy
• Degenerative spinal disease
• Scoliosis
• Spinal tumors
• Spinal fracture
• Spinal infection
• Spinal deformity
• Minimally invasive orthopedic surgery
• Osteoporosis
• Orthopedic trauma
• Osteoarthritis
LANGUAGES SPOKEN：
• English
• Chinese

 

• School of Medicine, College of Medicine, Taipei Medical University, Taipei city, Taiwan

• Doctoral degree, Graduate Institute of Clinical Medicine Sciences, Chang-Gung University, Taiwan

Professional Experience:

• Attending Physician, Department of Orthopedics Surgery, Spine Surgery Section, Chang-Gung Memorial Hospital, Chiayi, Taiwan

Lecturer (Department of Orthopaedic Surgery, Chang-Gung Memorial Hospital, Chiayi, 2012/8-2015/6)

Associate editor, Clinical diagnostics and imaging, BMC Musculoskeletal Disorders (2018 IF: 2.002)

Visiting staff, TMU Research Center of Biomedical Devices Prototyping Production

AOPEER teacher, AO Clinical Investigation and Documentation (AOCID) and the AO Education Institute (AOEI)

Committee member, Joint Institutional Review Board, Taipei Medical University (2020/1/1~)

Certification:

• Advanced Trauma Life Support (ATLS)

• Advanced Cardiovascular Life Support (ACLS)

• International Society for Clinical Densitometry (ISCD)

Board of Certification:

• Board of Orthopaedics, Taiwan Orthopaedic Association (Member No. 1732)

• Board of Osteoporosis, Taiwan Osteoporosis Association (Member No. 340)

Professional Membership Societies：

• Taiwan Society of Endoscopic Spine Surgery, board member

• Taiwan Medical Design Association, board member

• Taiwan Orthopaedic Association, member 

• Taiwan Spine Society, member

• Taiwan Society of Minimally Invasive Spine Surgery, member

• Taiwan Orthopedic Research Society, member

• Taiwan Osteoporosis Association, member

• Taiwan Society of Spine Endoscopy Surgery, member

• AOSpine, Silver member

• North American Spine Society, member

• Spine section of the APOA (APSS), Life Fellow

• Société Internationale de Chirurgie Orthopédique et de Traumatologie a.i.s.b.l. (SICOT) active member, Committee member of Young Surgeon Committee.

Fellowships

• Visiting Research Fellowship at Rothman Institute, Thomas Jefferson University, Philadelphia, USA (2014-1-6 to 2014-2-13): Sponsored by Government project (Clinical trials for medical devices)

• APSS Depuy-Synthes Clinical Fellowship 2015 at Department of Orthopedics and Traumatology, The University of Hong Kong, China (2015-5-18 to 2015-6-7)

• AOSpine East Asia Clinical Fellowship 2016 at Seoul St. Mary Hospital, the Catholic University of Korea, South Korea (2016-9-5 to 2016-10-21)

• Global Faculty in Training (GFIT) Program 2020 at Stanford Byers Center for Biodesign, Stanford University (2020-1-7 to 2020-6-12)

 

Publications ：

1. Role of the supine lateral radiograph of the spine in vertebroplasty for osteoporotic vertebral compression fracture: a prospective study. MH Wu, TJ Huang, CC Cheng, YY Li, RW Hsu. BMC Musculoskelet Disord. 2010 Jul 19;11:164. (SCI)
2. Candidal arthritis in revision knee arthroplasty successfully treated with sequential parenteral-oral fluconazole and amphotericin B-loaded cement spacer. MH Wu, KY Hsu. Knee Surg Sports Traumatol Arthrosc. 2011 Feb;19(2):273-6. (SCI)
3. A Comparison of Three Types of Postoperative Pain Control after Posterior Lumbar Spinal Surgery. MH Wu, CH Wong, CC Niu, TT Tsai, LH Chen, WJ Chen. Spine (Phila Pa 1976). 2011 Feb 15. (SCI)
4. Single portal endoscopic carpal tunnel release: modification of Menon's technique and data from 65 cases. 

Chen AC, MH Wu, CH Chang, CY Cheng, KY Hsu. Int Orthop. 2011 Jan;35(1):61-5. MH Wu, TJ Huang, YY Li, CC Cheng, KC Huang, Robert WW Hsu. Formosan Journal of Musculoskeletal Disorders 2012 3:39-42. 

5. Complications of cement-augmented dynamic hip screws in unstable type intertrochanteric fractures - a case series study. MH Wu, PC Lee, KT Peng, CC Wu, TJ Huang, RW Hsu. Chang Gung Med J. 2012 Jul;35(4):345-53. (SCI)
6. Intraoperative Computed Tomography with Integrated Navigation in Percutaneous Iliosacral Screwing. KT Peng, YY Li, WH Hsu, WH Wu, JT Yang, CH Hsu, TJ Huang. Injury. 2013 Feb;44(2):203-8. (SCI)

7. Comparing radiation exposure during percutaneous vertebroplasty using one- vs. two-fluoroscopic technique. Li YY, Huang TJ, Cheng CC, Wu MH, Lee CY. BMC Musculoskelet Disord. 2013 Jan 22;14:38. (SCI)

8. Comparison of Minimal Access and Traditional Anterior Spinal Surgery in Managing Infectious Spondylitis. A Minimum Two-Year Follow-up. CY Lee, YY Li, TJ Huang, CC Cheng, and MH Wu. Spine Journal, Jul. 2013. (SCI)
9. Intraoperative computed tomography navigation for transpedicular screw fixation to treat unstable thoracic and lumbar spine fractures: clinical analysis of a case series (CARE-compliant). CY Lee, MH Wu, YY Li, CC Cheng, CH Hsu, TJ Huang, RW Hsu. Medicine (Baltimore). 2015 May;94(20):e757. (SCI)
10. Treatment outcome of fungal vertebral osteomyelitis – a case series study and literature review.
    MH Wu, TY Huang, TJ Huang, CY Lee, YY Li, C C Cheng, Mel Lee, Robert WW Hsu. Formosan Journal of Musculoskeletal Disorders. 2015, 6, 89-97.
11. Infectious Spondylitis-Associated Staphylococcus aureus with Virulence Gene pvl or tst Causes More Necrosis than Apoptosis in Human Alveolar Basal Epithelial Cell Line A549. TJ Huang, CH Lee, MH Wu, YY Li, TH Yang, CC Cheng, CY Lee, CC Lu, CS Chu. Advances in Microbiology 2016, 06(07):479-488
12. Comparison of gram-negative and gram-positive hematogenous pyogenic spondylodiscitis: clinical characteristics and outcomes of treatment. Ching-Yu Lee, MH Wu, CC Cheng, TJ Huang, TY Huang, CY Lee, JC Huang, YY Li. BMC Infect Dis. 2016; 16: 735. Published online 2016 Dec 6. doi: 10.1186/s12879-016-2071-4 (SCI)
13. Intraoperative computed tomography navigation for transpedicular screw placement in posterior instrumentation and correction of adolescent idiopathic scoliosis. YY Li, CY Lee, MH Wu, TJ Huang, CC Cheng, CY Lee. Formosan Journal of Musculoskeletal Disorders 7 (2016) 57-62
14. Video-Assisted Thoracoscopic Surgery and Minimal Access Spinal Surgery Compared in Anterior Thoracic or Thoracolumbar Junctional Spinal Reconstruction: A Case-Control Study and a Review of the Literature. CY Lee, MH Wu, YY Li, CC Cheng, CY Lee, and TJ Huang. BioMed Research International, 2016, Article ID 6808507 (SCI)

15. Outcomes and Satisfaction with Endoscopic Carpal Tunnel Releases and the Predictors - A Retrospective Cohort Study. Alvin CY Chen, MH Wu, CY Cheng, YS Chan. The Open Orthopaedics Journal 2016 Dec 10(1):757-764
16. Application of intraoperative CT-guided navigation in simultaneous minimally invasive anterior and posterior surgery for infectious spondylitis.
    MH Wu, NK Dubey, CY Lee, YY Li, CC Cheng, CS Shi, and TJ Huang. BioMed Research International. 2017, Volume 2017, Article ID 2302395. (SCI)
17. Comparison of minimally invasive spine surgery using intraoperative computed tomography integrated navigation, fluoroscopy and conventional open surgery for lumbar spondylolisthesis: a prospective registry-based cohort study. MH Wu, NK Dubey, YY Li, CY Lee, CC Cheng, CS Shi, and TJ Huang. Spine J. 2017 Volume 17, Issue 8, Pages 1082–1090 (SCI)

18. Validate a two-step multiplex PCR in detecting pathogens of vertebral osteomyelitis. Focus on Mycobacterium tuberculosis. CS Chu; TJ Huang; PY Lin; YY Li; MH Wu; TH Yang; CC Cheng; CY Lee. Formosan Journal of Musculoskeletal Disorders 8 (2017) 66-74
19. Magnetic Resonance-Guided Focused Ultrasound Versus Conventional Radiation Therapy for Painful Bone Metastasis: A Matched-Pair Study. HL Lee, CC Kuo, JT Tsai, CY Chen, MH Wu, JF Chiou. J Bone Joint Surg Am. 2017 Sep 20;99(18):1572-1578. doi: 10.2106/JBJS.16.01248. (SCI)
20. Evaluation of a Novel Biodegradable Thermosensitive Keto-Hydrogel for Improving Postoperative Pain in a Rat Model. MH Wu, MH Shih, WB Hsu, NK Dubey, WF Lee, TY Lin, MY Hsieh, CF Chen, KT Peng, TJ Huang, CS Shi, RS Guo, CJ Cai, CY Chung, CH Wong. PLoS One 2017, Oct 23;12(10):e0186784. doi: 10.1371/journal.pone.0186784. eCollection 2017. (SCI)
21. Postoperative Infection in Patients Undergoing Posterior Lumbosacral Spinal Surgery: A Pictorial Guide for Diagnosis and Early Treatment. SH Chen, WJ Chen, MH Wu, JC Liao, CJ Fu. Clin Spine Surg. 2018 Jul;31(6):225-238. (SCI)
22. Cement-Augmented Pedicle Screw Insertion Assisted by Spinal Robotic Systems for Widespread Spinal Metastases: A Case Report. Christopher Wu, CY Lee, MD, TJ Huang, MH Wu*. J Robot Surg. 2018. DOI: 10.1007/s11701-018-0886-2.
23. Preparation and in vitro bioactivity of micron-sized bioactive glass particles using spray drying method. Yu-Jen Chou, Chih-Wei Hsiao, Nien-Ti Tsou, MH Wu, Shao-Ju Shih. Applied Sciences. 2019, 9, 19. (SCI)
24. MLN4924, a protein neddylation inhibitor, suppresses the growth of human chondrosarcoma through inhibiting cell proliferation and inducing endoplasmic reticulum stress–related apoptosis. MH Wu, Ching-Yu Lee, Tsung-Jen Huang, Kuo-Yuan Huang, Chih-Hsin Tang, Shing-Hwa Liu, Kuan-Lin Kuo, Feng-Che Kuan, Wei-Chou Lin, Chung-Sheng Shi* Int. J. Mol. Sci. 2019, 20, 72. (SCI)
25. Retrieval of a Broken Surgical Scalpel Blade with a Dangerous Anterior Migration in Treating a Herniated Disk along with an Osteophyte: A Case Report. Christopher Wu, Meng-Huang Wu (Co-first author), Ching-Yu Lee, Yen-Yao Li, Tsung-Jen Huang. Formosan Journal of Musculoskeletal Disorders, 2019, in press（No.178-1070915).
26. Multi-scale Mapping for Collagen-regulated Mineralization in Bone Remodeling of Additive Manufacturing Porous Implants. Pei-I Tsai; Tu-Ngoc Lam; Meng-Huang Wu (2nd author); Kuan-Ying Tseng; Yuan-Wei Chang; Jui-Sheng Sun; Yen-Yao Li; Ming-Hsueh Lee; San-Yuan Chen; Chung-Kai Chang; Chun-Jen Su; Chia-Hsien Lin; Ching-Yu Chiang; Ching-Shun Ku; Nien-Ti Tsou; Shao-Ju Shih; Chun-Chieh Wang; E-Wen Huang. Materials Chemistry and Physics, Volume 230, 15 May 2019, Pages 83-92 (SCI)
27. Risk factors of synchronous multifocal necrotizing fasciitis: a case control study in comparison with monofocal necrotizing fasciitis in Taiwan. Ching-Yu Lee, Tsan-Wen Huang, Meng-Huang Wu, Tsung-Jen Huang, Yan-Rong Li, Evelyn Jou-Chen Huang*, Yao-Hung Tsai*. BMC Infectious Diseases (2019) 19:513. (SCI)
28. 肌少症在脊椎疾病與脊椎手術中扮演的角色. 郭又愷、Meng-Huang Wu^*. Taiwan Bone Muscle Joint Total Care Association 2019, 6.
29. High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures. Ching-Yu Lee, Tsung-Jen Huang*, Meng-Huang Wu, Yen-Yao Li, Kuan-Der Lee. BioMed Research International. 2019,8. Article ID 4714279. (SCI)
30. The Effects of Different Dynamic Culture Systems on Cell Proliferation and Osteogenic Differentiation in Human Mesenchymal Stem Cells. Hsiou-Hsin Tsai†, Kai-Chiang Yang†, Meng-Huang Wu, Jung-Chih Chen,* Ching-Li Tseng *. Int. J. Mol. Sci. 2019, 20(16), 4024. (SCI)
31. Full-endoscopic lumbar foraminoplasty for symptomatic cement leakage with exiting nerve root impingement. Christopher Wu, Ching-Yu Lee, Tsung-Jen Huang, Meng-Huang Wu*. World Neurosurgery, 2019, in press. (SCI)
32. Prognostic and predictive factors for clinical and radiographic responses in patients with painful bone metastasis treated with magnetic resonance-guided focused ultrasound surgery. Tsai YC, Lee HL, Kuo CC, Chen CY, Hsieh KL, Wu MH, Wen YC, Yu HW, Hsu FC, Tsai JT, Chiou JF. Int J Hyperthermia. 2019;36(1):932-937. (SCI)
33. Preparation and Characterization of Chemically TEMPO-oxidized and Mechanically Disintegrated Sacchachitin Nanofibers (SCNF) for Enhanced Diabetic Wound Healing. Fang-Ching Chao, Meng-Huang Wu (Co-First author), Ling-Chun Chen, Hong-Liang Lin, Der-Zen Liu, Hsiu-O Ho, and Ming-Thau Sheu*. Carbohydrate Polymers. 2019, 10, in press. (SCI)
34. Simultaneous Bilateral Total Knee Arthroplasty Becomes Safer After Institution of Optimal Perioperative Management—a Longitudinal Cohort Study. Shih-Hao Chen, Jen-Yuh Chen, Tze-Hong Wong, Frederick Buechel Jr. , Meng-Huang Wu*. Journal of Knee Surgery. 2019, In press. (SCI)