Yi-Wen (Even) Huang, M.D., Ph.D.

Gastroenterology

SPECIALTY/PRACTICE AREAS：
• Hepatitis B, C, D; Fatty liver
• Liver tumor; Chronic liver disease; Cirrhosis
• Gastrointestinal and Biliary Pancreatic disorders
LANGUAGES SPOKEN：
• English
• Chinese

 

PROFESSIONAL EDUCATION：

• Ph.D., Graduate Institute of Clinical Medicine, National Taiwan University
• M.D., School of Medicine, China Medical University, Taiwan

 

ADMINSTRATIVE APPOINTMENTS：

• Hepatologist; Gastroenterologist; Endoscopis
• Liver oncologist; Internist; Sonographer
• New drug investigator
• Medical school faculty; Journal editor

 

PUBLICATIONS：

• Shih-Jer Hsu, Yi-Wen Huang, Wan-Long Chuang. Ropeginterferon Alfa-2b Administered Every Two Weeks for Patients with Genotype 2 Chronic Hepatitis C. Journal of the Formosan Medical Association 2021;120:956-64.
• Yi-Wen Huang, Pei-Jer Chen. Ropeginterferon Alfa-2b Every Two Weeks as a Novel Pegylated Interferon for Patients with Chronic Hepatitis B. Hepatology International 2020;14:997-1008.
• Bo-Yuan Huang, Yi-Wen Huang, Ming-Whei Yu. Longitudinal change of metabolite profile and its relation to multiple risk factors for the risk of developing hepatitis B-related hepatocellular carcinoma. Molecular Carcinogenesis 2020;59:1269-79.
• Ya-Hui Wang, Yi-Wen Huang, Ming-Whei Yu. Smoking and hepatitis B virus-related hepatocellular carcinoma risk: the mediating roles of viral load and alanine aminotransferase. Hepatology 2019;69:1412.
• Yi-Wen Huang, Sien-Sing Yang. New onset diabetes increases risk for hepatic encephalopathy in cirrhotics with ascites: a nationwide cohort study. Advances in Digestive Medicine 2019;6:93-100.
• Chien-Chao Chiu, Yi-Wen Huang, Hsiao-Li Chuang. Nonalcoholic fatty liver disease is exacerbated in high-fat diet-fed gnotobiotic mice by colonization with the gut microbiota from patients with nonalcoholic steatohepatitis. Nutrients 2017;9:E1220. doi:10.3390/nu9111220.
• Yi-Hsun Chen, Yi-Wen Huang, Hsiao-Li Chuang, Ter-Hsin Chen. Effects of plant- and animal-based high-fat diets on lipid storage and distribution in environmental bacteria-colonized gnotobiotic mice. Biochemical and Biophysical Research Communications 2017;493:1075-1081.
• Ruei-Hsin Chang, Yi-Wen Huang, Rui-Ting Hu, Sien-Sing Yang. Long-term nucleos(t)ides analogues for chronic hepatitis B improve liver and spleen size: a noninvasive sonographic study. Journal of Medical Ultrasound 2017;25:161-166.
• Yi-Wen Huang. Multidisciplinary approach to optimize management of patients with chronic hepatitis C and alcoholic liver disease. Journal of the Formosan Medical Association 2016;115:1097-1098.
• Yi-Wen Huang, Ding-Shinn Chen. Statins reduce the risk of cirrhosis and its decompensation in chronic hepatitis B patients: A nationwide cohort study. The American Journal of Gastroenterology 2016;111:976-985. doi: 10.1038/ajg.2016.179.
• Yi-Wen Huang, An-Chi Hsieh, Sien-Sing Yang. Statins and the risk of cirrhosis and its decompensation in chronic hepatitis B patients. The American Journal of Gastroenterology 2016;111:1655-1656.
• Yi-Wen Huang, An-Chi Hsieh, Sien-Sing Yang. Statins reduce the risk of cirrhosis and its decompensation in CHB patients? – authors’ reply. The American Journal of Gastroenterology 2017;112:383-384.
• Yi-Wen Huang, An-Chi Hsieh, Sien-Sing Yang. Safety of statins in chronic hepatitis B patients. The American Journal of Gastroenterology 2017;112:385-386.
• Yi-Wen Huang, An-Chi Hsieh, Sien-Sing Yang. Did statins really reduce the risk of cirrhosis and decompensation in chronic hepatitis B patients? – authors’ reply. The American Journal of Gastroenterology 2017;112:387-388.
• Tung-Hung Su, Yi-Wen Huang, Jia-Horng Kao and on behalf of the C-TEAM study group and the Taiwan Liver Diseases Consortium. Four-year entecavir therapy reduces hepatocellular carcinoma, cirrhotic events and mortality in chronic hepatitis B patients. Liver International 2016;36:1755-1764.
• Yi-Wen Huang, Chun-Jen Liu, Jia-Horng Kao, Ding-Shinn Chen. Increased risk of hepatocellular carcinoma in chronic hepatitis C patients with new onset diabetes: A nationwide cohort study. Alimentary Pharmacology and Therapeutics 2015;42:902-911.
• Szu-Chieh Fu, Yi-Wen Huang, Sien-Sing Yang. Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with new onset diabetes: A nationwide cohort study. Alimentary Pharmacology and Therapeutics 2015;41:1200-1209.
• Szu-Chieh Fu, Yi-Wen Huang. Editorial: Diabetes and its association with hepatocellular carcinoma in chronic hepatitis B – authors’ reply. Alimentary Pharmacology and Therapeutics 2015;42:118-119.
• Yi-Wen Huang, Kazuaki Chayama, Jia-Horng Kao, Sien-Sing Yang. Detectability and clinical significance of serum hepatitis B virus ribonucleic acid. Hepatobiliary Surgery and Nutrition 2015;4:197-202. doi: 10.3978/j.issn.2304-3881.2014.11.08.
• Yi-Wen Huang, Jia-Horng Kao. Increased risk of cirrhosis and its decompensation in chronic hepatitis C patients with new onset diabetes: A nationwide cohort study. Hepatology 2014;60:807-14.
• • Yi-Wen Huang, Jia-Horng Kao. Reduced Toll-like receptor-9 expression on peripheral CD14+ monocytes of chronic hepatitis B patients and its restoration by effective therapy. Antiviral Therapy 2014;19:637-643; doi:10.3851/IMP2762.
• Yi-Wen Huang, Sien-Sing Yang, Jia-Horng Kao. Reply to: Modulation of Toll-like receptor 9 expression on monocytes of viral hepatitis patients. Antiviral Therapy 2015;20:669-70.
• Yi-Wen Huang, Shoichi Takahashi, Masataka Tsuge, Kazuaki Chayama, Jia-Horng Kao. On-treatment low serum HBV RNA level predicts initial virological response in chronic hepatitis B patients receiving nucleoside analogues therapy. Antiviral Therapy 2015;20:369-375 (doi: 10.3851/IMP2777).
• Yi-Wen Huang, Jia-Horng Kao. Increased risk of cirrhosis and its decompensation in chronic hepatitis B patients with newly diagnosed diabetes: A nationwide cohort study. Clinical Infectious Diseases 2013;57:1695-702.
• Dahlene N. Fusco, Yi-Wen Huang, Raymond T. Chung, Abraham L. Brass. A genetic screen identifies interferon-alpha effector genes required to suppress hepatitis C virus replication. Gastroenterology 2013;144:1438-49.
• Yi-Wen Huang, Jia-Horng Kao. Reduced Toll-like receptor-3 expression in chronic hepatitis B patients and its restoration by interferon therapy. Antiviral Therapy 2013;18:877-84.
• Yi-Wen Huang, Sien-Sing Yang, Ding-Shinn Chen. Biphasic pattern of depression and its predictors during pegylated interferon-based therapy in chronic hepatitis B and C patients. Antiviral Therapy 2013;18:567-73.
• Yi-Wen Huang, Raymond T. Chung. Management of hepatitis B reactivation in patients receiving cancer chemotherapy. Therapeutics Advances in Gastroenterology 2012;5:359-70.
• Tai-Chung Tseng, Yi-Wen Huang, Jia-Horng Kao. Effect of host and viral factors on hepatitis B e antigen-positive chronic hepatitis B patients receiving pegylated interferon-α-2a therapy. Antiviral Therapy 2011;16:629-37.
• Yi-Wen Huang, Sien-Sing Yang, Jia-Horng Kao. Pathogenesis and management of alcoholic liver cirrhosis: a review. Hepatic Medicine 2011;3:1-11.
• Chih-Wen Lin, Yi-Wen Huang, Mei-Yu Hsu, Sien-Sing Yang. Esophagogastric varices predict mortality in hospitalized patients with alcoholic liver disease in Taiwan. Hepato-Gastroenterology 2010;57:305-8.
• Tung-Hung Su, Yi-Wen Huang, Jia-Horng Kao. Serum hepatitis B surface antigen concentration correlates with HBV DNA level in patients with chronic hepatitis B. Antiviral Therapy 2010;15:1133-9.
• Yi-Wen Huang, Jui-Ting Hu, Sien-Sing Yang. Complications of alcoholic liver cirrhosis: active assessment by endoscopy and sonography. Hepatology 2010;52:1864-1865.
• Yi-Wen Huang, Kazuaki Chayama, Masataka Tsuge, Shoichi Takahashi, Jia-Horng Kao. Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B. Antiviral Therapy 2010;15:177-184.
• Yi-Wen Huang, Ya-Tang Liao, Wendy Chen, Jia-Horng Kao. Vitamin D receptor gene polymorphisms and distinct clinical phenotypes of hepatitis B carriers in Taiwan. Genes and Immunity 2010;11:87-93.
• Sien-Sing Yang, Jui-Ting Hu, Yi-Wen Huang, Mei-Yu Hsu, Han-Yu Chang. The study of narrow band imaging system in the evaluation of esophageal varices. Gastroenterology Journal of Taiwan 2009;26:164-169.
• Yi-Wen Huang, Chung-Yi Hu, Jia-Horng Kao. Human leukocyte antigen-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus. Journal of Medical Virology 2009;81:588-593.
• Yi-Wen Huang, Chih-Lin Lin, Pei-Jer Chen, Ming-Yang Lai, Jia-Horng Kao, Ding-Shinn Chen. Hepatitis B viral genotype in Taiwanese patients with acute hepatitis B. Hepato-Gastroenterology 2008; 55: 633-35.
• Yi-Wen Huang, Chun-Jen Liu, Ming-Yang Lai, Po-Huang Lee, Meng-Kung Tsai, Shoei-Shen Wang, Ming-Kuen Lai, Jia-Horng Kao. Discontinuation of lamivudine treatment for hepatitis flare after kidney or heart transplant in hepatitis B surface antigen positive patients: a retrospective case series. Clinical Therapeutics 2006; 28(9): 1327-34.
• Yi-Wen Huang, Chih-Lin Lin, Pei-Jer Chen, Ming-Yang Lai, Jia-Horng Kao, Ding-Shinn Chen. Higher cut-off index value of immunoglobulin M antibody to hepatitis B core antigen in Taiwanese patients with hepatitis B. Journal of Gastroenterology and Hepatology 2006; 21(5): 859-62.